The sphincter of Oddi is a muscle that opens and closes to allow bile and pancreatic juice to flow between the pancreas and the small intestine. In Sphincter of Oddi dysfunction, the sphincter muscle does not open when it should. Which causes a backup of digestive juices and severe pain in the abdomen.

This condition is treated with medications or a procedure called a sphincterotomy.

Because this is a muscular problem,Iit is not beyond the realms of possibility that it could become associated with Multiple Sclerosis.

While there is not enough proof that sphincter of Oddi dysfunction plays a causative role in MS, it does raise the possibility. This condition has not yet been proven, but it is worth further study.

Sphero, another alternative toy master, has a similar feature. They make a tiny, escape-riding droid called the Lemp. Apparently, it’s also connected to a moving part in the electronic brain: the sphincter of Oddi. Perhaps sphincter of Oddi is involved in the control of robot movement, or guiding the path from the inside to the outside.

The sphincter of Oddi is the unravelling center of the gastrointestinal tract. That acts as a gateway for bile, pancreatic juice, and other digestive fluids. And aids in the movement of food through the digestive tract.


Spasms of the sphincter of Oddi can also be a sign of generalized inflammation of the pancreas. That may be caused by M.S. or Diabetes.

This inflammation can lead to significant damage to the pancreas. Which may explain why sphincter of Oddi spasms are often life threatening.

Sphincter of Oddi Dysfunction

It has to be mentioned that although this condition can be observed in both men and women. Most patients with sphincter of Oddi find that it occurs in years, rather than in one night. Possibly after eating strange foods.

Inflammation of the Pancreas

This could be because the emptying of the stomach by the small intestines is too slow. To allow the bile to flow through and along the sphincter muscle. Severe spasms are often associated with anemia, which can start in the abdomen and travel to the liver.

It is good news that researchers are beginning to understand how this condition originates. And how treatments can be developed to limit its effect.

The sphincter of Oddi and its surrounding muscles also play a major role in producing stomach acid. Normally the acid secretions cause stomach cramps and pain when swallowed.

However, if the sphincter of Oddi cannot function normally, acid secretion is less regular. And stomach acid production is even more intense because there is not enough sphincter muscle function. To allow refluxed acids back up to the stomach. This condition can lead to significant intestinal discomfort. It is common to have a feeling of “gut-churn” when we eat as a part of a normal digestive process. After eating, stomach contents move to the small intestine where they can be propelled through the process of stomach emptying.

The amount of stomach content that passes through the muscle of the sphincter can differ, depending. On how much food is eaten and the contractions associated with stomach pumping. Usually, less stomach content passes through the sphincter of Oddi. This condition described by researchers is known as Common Gastric Hypercarsis.

Movement of Chime

However, many patients with sphincter of Oddi have a normal amount of stomach content. When the emptying process does not occur as it should,. Ad sphincter of Oddi spasms result, then Common Gastric Hypercarsis could be a sign of MS.

Pancreatic Juices

Common Gastric Hypercarsis usually arises due to a decrease in the level of stomach acid. With symptoms appearing around the 6th day after a meal. This condition is now known as Barrett’s Munchausen syndrome. And involves the contraction of the sphincter of Oddi and valves that let food pass through into the small intestine.

Certain medications and surgical procedures can be used to treat Barrett’s Munchausen syndrome. My understanding is that sphincter of Oddi dysfunction occurs most commonly in people with MS. Who often have no other clear centers for digestive/respiratory care.

There have been reports that the sphincter can become chronically activated in people with MS. As MS progresses and there is more severe symptom associated motor weakness, the sphincter becomes overactive causing pain.

If you were to see me in this state — I would am very concerned about your health!

I believe that the same sphincter that controls the acidity (uric acid) of the stomach. Also controls the dynamics of the pancreas. The pancreas produces two types of hormones, secretin and actin.

If the pancreas is not in a normal state, it makes the risk of cancer very real. People with MS tend to have lower levels of both actin and secretin. This leads to the typical pancreas, with fatty deposits and less capacity to make hormones.

Immune System Attack

MS is a chronic autoimmune disease, meaning the body’s immune system attacks its own tissue, specifically the brain.

Cells lining the pancreas get damaged and fluid fills up in the cells. Which should allow the pancreas to function normally.

Instead, these damaged cells react with increased secretin, which in turn tightens up the sphincter. And prevents the pancreas from taking its normal cues from the stomach, causing spasms and pain.

This condition is called Endocrine Gland Dysfunction in MS. Many medications are used to treat MS and for different symptoms. Like pain and spasms in the arms and legs that cause fatigue, cognitive dysfunction, and some speech issues.

Unfortunately many medications associated with MS are also used for this condition. Endocrine Gland Dysfunction has been found in up to 75% of individuals with active MS.

Integrating all these different symptoms and side effects can be an enigmatic and tough task. Especially when there are no natural markers supporting diagnosis.

People must search high and low to find natural markers for MS. And even diseases that often go unseen in medical examination. Neuropathy or nerve pain associated with MS typically begins abruptly and is generally untreated from an early age. It most typically shows as sudden onset weakness or numbness of the feet, hands or legs.

The resourceful will begin to massage the area with ice until the pain subsides. It is not uncommon to find that this is followed by burning pain or tingling in the affected extremities; along with other sensory loss.

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